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抗いもち剤探索のケミカルバイオロジー

Podophyllotoxin and α-peltatin inhibit nuclear factor κB activation and gene expression stimulated by a double-stranded RNA analogue in human umbilical vein endothelial cells

Identification of pyrrolizilactone biosynthetic gene cluster with unique short‐chain dehydrogenase gene for 3‐methylproline formation

Programmable synthesis of alkaloidal frameworks integrating Michael acceptor generates covalent probes for targeting POLE3 in HBV replication

Discovery of niclosamide as a p300/transcription factor protein-protein interaction inhibitor

Chemical screening of RIKEN natural products depository identified a MYCN expression inhibitor partially through HGF-MET signaling pathway

Diterpene molecular glue stabilizes protein-protein interactions of a disordered phosphoprotein that controls translational repression

HTD1265 disrupts GimC-dependent cellular processes in Saccharomyces cerevisiae

Novel ligands for the orphan receptor GPR151 modulate morphine action

Identification of a small molecule that targets activator of G-protein signaling 8