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Highly enantio- and diastereoselective synthesis of 1,2,3-trisubstituted cyclopropanes from α,β-unsaturated amides and stabilized sulffur ylides catalyzed by a chiral copper(I) complex.

2024年4月18日

Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment.

2024年4月18日

Concise and stereodivergent approach to chromanone lactones through copper-catalyzed asymmetric vinylogous addition of siloxyfurans to 2-ester-substituted chromones.

2024年4月18日

Synthesis and antiviral activity of formycin derivatives with anti-influenza virus activity.

2024年4月18日

Rediscovery of 4-trehalosamine as a biologically stable, mass-producible, and chemically modifiable trehalose analog.

2024年4月18日

Anti-influenza virus activity of methylthio-formycin distinct from that of T-705.

2024年4月18日

A missing link in multisubstituted pyrrolidines: remote stereocontrol forged by rhodium-alkyl nitrene.

2024年4月18日

Targeting the ATG5-ATG16L1 protein-protein interaction with a hydrocarbon-stapled peptide derived from ATG16L1 for autophagy inhibition.

2024年4月18日

Diastereoselective direct catalytic asymmetric Mannich-type reactions of alkylnitriles with a Ni(II)-carbene complex.

2024年4月18日

Synthesis of novobiocin derivatives and evaluation of their antigonococcal activity and pharmacokinetics.

2024年4月18日