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Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.

A cancer-specific monoclonal antibody against HER2 exerts antitumor activities in human breast cancer xenograft models.

A cancer-specific monoclonal antibody against podocalyxin exerted antitumor activities in pancreatic cancer xenografts.

Pancreatic stromal cell-derived oncostatin M confers drug resistance to a multi-tyrosine kinase Inhibitor in pancreatic cancer cells.

Identification of a small compound targeting PKM2-regulated signaling using 2D gel electrophoresis-based proteome-wide CETSA.