Compounds

Lentztrehalose A, B, C

Lentztrehalose A, B, C_1

Producing organism:

Lentzea sp.　ML457-mF8

Activity:

Enzyme-stable analog of trehalose (Antitumor, bone reinforcement, suppression of obesity)

Clinical use:

-

Class no:

4 Reference

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Title	Author	Journal	Year	Volume	Page
Structure and biological properties of lentztrehalose: a novel trehalose analog.	S. Wada, S. Ohba, T. Someno, M. Hatano and A. Nomoto.	J. Antibiot.	2014	67	319-322
Stability and bioavailability of lentztrehaloses A, B, and C as replacements for trehalose	S. Wada, R. Sawa, S. Ohba, C. Hayashi, M. Umekita, Y. Shibuya, K. Iijima, F. Iwanami and M. Igarashi	J. Agric. Food Chem.	2016	64	7121-7126
Novel autophagy inducers lentztrehaloses A, B and C.	S. Wada, Y. Kubota, R. Sawa, M. Umekita, M. Hatano, S. Ohba, C. Hayashi, M. Igarashi, and A. Nomoto	J. Antibiot.	2015	68	521-529
Synthesis and determination of absolute configuration of lentztrehalose A.	M. Zhang, S. Wada, F. Amemiya, T. Watanabe, and M. Shibasaki	Chem. Pharm. Bull.	2015	63	961-966