Compounds

Amycolamicin

Amycolamicin_1

Producing organism:

Amycolatopsis. sp. MK575-fF5

Activity:

Antibacterial (Inhibition of bacterial type II topoisomerases)

Clinical use:

-

Class no:

-

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Title Author Journal Year Volume Page
Biosynthesis of amycolamicin: the biosynthetic origin of a branched α-aminoethyl moiety in the unusual sugar amycolose. S. Tohyama, Y. Takahashi and Y. Akamatsu. J. Antibiot. 2010 63 147-149.
Amycolamicin, a new broad-spectrum antibiotic inhibiting bacterial topoisomerase. R. Sawa, Y. Takahashi, H. Hashizume,　K. Sasaki,　Y. Ishizaki,　M. Umekita,　M. Hatano,　H. Abe,　T. Watanabe,　N. Kinoshita,　Y. Homma, C. Hayashi,　K. Inoue,　S. Ohba,　
T. Masuda,　 M. Arakawa,　Y. Kobayashi,　M. Hamada,　M. Igarashi,　H. Adachi,
Y. Nishimura and Y. Akamatsu.		 Chem. Eur. J. 2012 in press