Compounds

Mannostatin

Mannostatin_1

Producing organism:

Streptoverticillium verticillus var. quintum ME3-AG3

Activity:

-

Clinical use:

-

Class no:

6 Reference(s)

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Title	Author	Journal	Year	Volume	Page
Mannostatins A and B: new inhibitor of α-D-mannosidase, produced by Streptoverticillium verticillus var. quintum ME3-AG3: taxonomy, production, isolation, physico-chemical properties and biological activities.	T. Aoyagi; T. Yamamoto; K. Kojiri; H. Morishima; M. Nagai; M. Hamada; T. Takeuchi; H. Umezawa	J. Antibiotics	1989	42	883-889
Structure determination of mannostatins A and B.	H. Morishima; K. Kojiri; T. Yamamoto; T. Aoyagi; H. Nakamura; Y. Iitaka	J. Antibiotics	1989	42	1008-1011
Mannostatin A, a new glycoprotein-processing inhibitor.	J. E. Tropea; G. P. Kaushal; I. Pastuszak; M. Mitchell; T. Aoyagi; R. J. Molyneux; A. D. Elbein	Biochemistry	1990	29	10062-10069
Inhibiton of tumor cell invasion in the Boyden chamber assay by a mannosidase inhibitor, mannostatin A.	Y. Ochi; S. Atsumi; T. Aoyagi; K. Umezawa	Anticancer Research	1993	13	1421-1424
Flexible enantiodivergent synthesis and biological activity of mannostatin analogues, new cyclitol glycosidase inhibitors.	Y.Nishimura; Y. Umezawa; H. Adachi; S. Kondo; T. Takeuchi	J. Organic Chemistry	1996	61	480-488
Synthesis of mannostatins and cyclophellitols, new cyclitol inhibitors for glycoside metabolism of glycoproteins and glycolipids.	Y. Nishimura	Studies in Natural Products Chemistry, Vol. 19, Structure and Chemistry (Part E), Elsevier (Editor: Atta-ur-Rahman)	1997	19	351-387