Institute  of  Microbial  Chemistry


  • Jul. 9, 2021

    Discovery of a mechanism for efficient autophagosome formation
    ~Revealing the molecular role of the most famous autophagy factor~


  • Oct. 27, 2020

    Elucidation of the mechanism of autophagosomal membrane expansion
    ~Disclosure of the function of Atg9, the most mysterious protein in autophagy~


  • Jan. 29, 2020

    Liquidity Is a Critical Determinant for Selective Autophagy of Protein Condensates


  • Sep. 10, 2019

    We are pleased to announce that Dr. Christopher R. Opie, a researcher in the Department of Organic Synthesis Research, won a Poster Award at the 27th International Society of Heterocyclic Chemistry (ISHC) Congress.
    "Systematic Examination of Catalytic Amide Bond Formation by the Readily Accessible B3NO2 Heterocycle-Containing Molecule Pym-DATB"

  • Mar. 28, 2019

    As a related event in the 60th Science and Technology Week in 2019, we will hold a special exhibition of Hamao Umezawa Memorial Museum Meguro (HUM) on April 15 (Mon)-20 (Sat).


  • Mar. 26, 2019

    Elucidation of the molecular mechanisms of providing phospholipids as building blocks for autophagosome formation
    ~Solving a historical riddle in the field of autophagy~


  • Oct. 15, 2018

    Former Chairman of MCRF, Dr. Tamio Yamakawa (5th MCRF Chairman, July 8, 2002 to March 31, 2011) passed away on October 7, 2018 (96 years old).
    Our deepest condolences to his family for their loss.

  • Oct. 11, 2018

    Collaborative research in the search for antibiotics field started at the IMC and KYORIN Pharmaceutical Co., Ltd.
    We have agreed to provide KYORIN Pharmaceutical Co., Ltd. with natural products and analogues thereof in the possession of the IMC
    and have started collaborative research in the search for antibiotics effective against multidrug-resistant bacteria.


  • Sep. 27, 2018

    The IMC has published an advertisement article on Nature Index 2018 Rising Stars feature of Nature magazine (Volume 561, Number 7723) September 29, 2018 issue. (page. S25) Please have a look. You can see the web version at the following URL.


  • Sep. 12, 2018

    We are pleased to inform you that Dr. Masayuki Igarashi (Head of Laboratory of Microbiology) received the Sumiki-Umezawa Memorial Award in 2018 relating to his research in the“Investigation of novel antibiotics effective against multidrug resistant bacteria”

    The lecture will be held at GakushiKaikan in Tokyo on November 8, 2018.


  • Mar. 23, 2018

    It was announced in the ”Nature Index 2018 Japan” of Nature magazine that IMC was determined to be the No. 1 research institution in Japan regarding high quality publications in natural sciences. This announcement reflects the large proportion of high quality scientific articles released by the institute in the six years from 2012 to 2017.


  • Feb. 2, 2018

    We are pleased to inform you that Dr. Naoya Kumagai (Chief Researcher) received the Merck-Banyu Lectureship Award 2017 in research on “A New Frontier of Amide Chemistry”.

  • Aug. 25, 2017

    We are pleased to announce the press release on development of anti-tuberculosis drug which shows effect on extensively drug resistant TB (XDRTB) discovered at our institute (IMC).


  • Apr. 6, 2017

    Honoring Professor Dr. Masakatsu Shibasaki’s 70th birthday, the Special Issue was published in HETEROCYCLES.

  • Jan. 31, 2017

    We have developed a new highly active catalyst for direct amidation.

    Uique physicochemical and catalytic properties dictated by the B3NO2 ring system.
    H. Noda, M. Furutachi, Y. Asada, M. Shibasaki, N. Kumagai
    Nat. Chem.
    doi: 10.1038/nchem.2708