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Decalpenic acid, a novel small molecule from Penicillium verruculosum CR37010, induces
early osteoblastic markers in pluripotent mesenchymal cells.
S. Sakamoto, F. Kojima, M. Igarashi, R. Sawa, M. Umekita, Y. Kubota, K. Nakae,
S.Yamaguchi, H. Adachi, Y. Nishimura and Y. Akamatsu.
J Antibio. 2010, 63, 703-708.
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Increased ABCB1 expression in TP-110-resistant RPMI-8226 cells.
M. Iijima, I. Momose and D. Ikeda.
Biosci Biotechnol Biochem. 2010, 74, 1913-1919.
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Structure-activity relationship of boronic acid derivatives of tyropeptin: proteasome
inhibitors.
T. Watanabe, H. Abe, I. Momose, Y. Takahashi, D. Ikeda and Y. Akamatsu.
Bioorg Med Chem Lett. 2010, 20, 5839-5842.
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Citric acid inhibits a bacterial ceramidase and alleviates atopic dermatitis in an animal
model.
H. Inoue, T. Someno, M. Kawada and D. Ikeda.
J Antibiot. 2010, 63, 611-613.
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NBRI16716A, a new antitumor compound against human prostate cancer cells, produced by
Perisporiopsis melioloides Mer-f16716.
M. Kawada, T. Someno, H. Inoue, S. Ohba, T. Masuda, T. Kato and D. Ikeda.
J Antibiot. 2010, 63, 319-323.
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NBRI17671, a new antitumor compound, produced by Acremonium sp. CR17671.
M. Kawada, I. Usami, T. Someno, T. Watanabe, H. Abe, H. Inoue, S. Ohba, T. Masuda,
Y.Tabata, S. Yamaguchi and D. Ikeda.
J Antibiot. 2010, 63, 237-243.
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Mitochondrial inhibitors show preferential cytotoxicity to human pancreatic cancer PANC-1
cells under glucose-deprived conditions.
I. Momose, S. Ohba, D. Tatsuda, M. Kawada, T. Masuda, G. Tsujiuchi, T. Yamori, H. Esumi
and D. Ikeda.
Biochem Biophys Res Commun. 2010, 392, 460-466.
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Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses
cancer metastasis.
S. Wada, I. Usami, Y. Umezawa, H. Inoue, S. Ohba, T. Someno, M. Kawada and D. Ikeda.
Cancer Sci. 2010, 101, 743-750.
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Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth
factor-I expression in prostate stromal cells.
M. Kawada, H. Inoue, S. Ohba, T. Masuda, I. Momose and D. Ikeda.
Int J Cancer. 2010, 126, 810-818.
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TP-110, a new proteasome inhibitor, down-regulates IAPs in human multiple myeloma
cells.
M. Iijima, I. Momose and D. Ikeda.
Anticancer Res. 2009, 29, 977-985.
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Synthesis of boronic acid derivatives of tyropeptin: proteasome inhibitors.
T. Watanabe, I. Momose, M. Abe, H. Abe, R. Sawa, Y. Umezawa, D. Ikeda, Y. Takahashi
and Y. Akamatsu.
Bioorg Med Chem Lett. 2009, 19, 2343-2345.
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New atpenins, NBRI23477 A and B, inhibit the growth of human prostate cancer cells.
M. Kawada, I. Momose, T. Someno, G. Tsujiuchi and D. Ikeda.
J Antibiot. 2009, 62, 243-246.
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Inhibitors of insulin-like growth factor-1 receptor tyrosine kinase are preferentially cytotoxic
to nutrient-deprived pancreatic cancer cells.
I. Momose, S. Kunimoto, M. Osono and D. Ikeda.
Biochem Biophys Res Commun. 2009, 380, 171-176.
-
Ceramidastin, a novel bacterial ceramidase inhibitor, produced by Penicillium sp.
Mer-f17067.
H. Inoue, T. Someno, T. Kato, H. Kumagai, M. Kawada and D. Ikeda.
J Antibiot. 2009, 62, 63-67.
-
Phthoxazolin A inhibits prostate cancer growth by modulating tumor-stromal cell
interactions.
M. Kawada, H. Inoue, I. Usami and D. Ikeda.
Cancer Sci. 2009, 100, 150-157.
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A new terrein glucoside, a novel inhibitor of angiogenin secretion in tumor angiogenesis.
M. Arakawa, T. Someno, M. Kawada and D. Ikeda.
J Antibiot. 2008, 61, 442-448.
-
Transforming growth factor-β1 modulates tumor-stromal cell interactions of prostate
cancer through insulin-like growth factor-I.
M. Kawada, H. Inoue, M. Arakawa and D. Ikeda.
Anticancer Res. 2008, 28, 721-730.
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A new proteasome inhibitor, TP-110, induces apoptosis in human prostate cancer PC-3
cells.
I. Momose, M. Iijima, M. Kawada and D. Ikeda.
Biosci Biotechnol Biochem. 2007, 71, 1036-1043.
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Highly tumorigenic human androgen receptor-positive prostate cancer cells overexpress
angiogenin.
M. Kawada, H. Inoue, M. Arakawa, K. Takamoto, T. Masuda and D. Ikeda.
Cancer Sci. 2007, 98, 350-356.
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Rakicidin A: a hypoxia-selective cytotoxin.
Y. Yamazaki, S. Kunimoto and D. Ikeda.
Biol Pharm Bull. 2007, 30, 261-265.
