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Title Authors Journal Year Vol Pages
ボロン酸を利用したがん分子標的治療薬の開発 百瀬 功、渡辺 匠 ファルマシア 2020 56 416-420
Interferon-induced transmembrane protein 1 (IFITM1) promotes distant metastasis of small cell lung cancer. S. Sakamoto, H. Inoue, Y. Kohda, S. Ohba, T. Mizutani, and M. Kawada Int. J. Mol. Sci. 2020 21 4934
Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. K. Mochida, A. Yamasaki, K. Matoba, H. Kirisako, N. N. Noda and H. Nakatogawa. Nat. Commun. 2020 11 3306
Liquid-liquid phase separation in autophagy. N. N. Noda, Z. Wang and H. Zhang. J. Cell Biol. 2020 219 e202004062
天然変性タンパク質によるオートファジー始動液滴の形成 藤岡優子、野田展生 生物物理 2020 60 171-173
An anti-human epidermal growth factor receptor 2 monoclonal antibody H2Mab-19 exerts antitumor activity in mouse colon cancer xenografts. Y. Kato, T. Ohishi, J. Takai, T. Nakamura, M. Sano, T. Asano, Y. Sayama, H. Hosono, M. Kawada and MK. Kaneko Monoclon Antib Immunodiagn Immunother. 2020 doi: 10.1089/mab.2020.0009
Direct catalytic asymmetric and anti-selective vinylogous addition of butenolides to chromones. J. Cui, N. Kumagai, T. Watanabe and M. Shibasaki Chemical Science. 2020 Accepted
カレントトピックス「液-液相分離によるオートファゴソームの形成部位の構築」
藤岡優子、野田展生 実験医学 2020 38 1354-1357
H2Mab-19 anti-human epidermal growth factor receptor 2 monoclonal antibody therapy exerts antitumor activity in pancreatic cancer xenograft models. Y. Kato, T. Ohishi, M. Sano, T. Asano, Y. Sayama, Y. Takei, M. Kawada and MK. Kaneko Monoclon Antib Immunodiagn Immunother. 2020 doi: 10.1089/mab.2020.0011.
Liquidity is a critical determinant for selective autophagy of protein condensates. A. Yamasaki, J. M. Alam, D. Noshiro, E. Hirata, Y. Fujioka, K. Suzuki, Y. Ohsumi and N. N. Noda Mol. Cell. 2020 77 1163-1175
Phase separation organizes the site of autophagosome formation. Y. Fujioka, J. M. Alam, D. Noshiro, K. Mouri, T. Ando, Y. Okada, A.I. May, R. L. Knorr, K. Suzuki, Y. Ohsumi and N. N. Noda Nature. 2020 578 301-305
Human ATG2B possesses a lipid transfer activity which is accelerated by negatively charged lipids and WIPI4.

T. Osawa, Y. Ishii and N. N. Noda Genes Cells.
2020 25 65-70
柔らかい構造の可視化①LLPSと膜動態を例に

能代大輔、野田展生 実験医学 2020 38 84-89
選択的オートファジーの構造生物学的基盤 野田展生 医学のあゆみ 2020 272 769-775
オートファゴソーム膜の供給③:蛋白質依存的な隔離膜への脂質供給機構 大澤拓生 医学のあゆみ 2020 272 730-736
オートファジーと液-液相分離


藤岡優子 医学のあゆみ 2020 272 763-768
Introduction of a 7-aza-6-MeO-indoline auxiliary in Lewis-acid/photoredox cooperative catalysis: highly enantioselective aminomethylation of α,β-unsaturated amides.

S. Kisan Pagire, N. Kumagai and M. Shibasaki Chemical Science 2020 11 5168-5174
Metacytofilin Is a Potent Therapeutic Drug Candidate for Toxoplasmosis Arpron Leesombun , Masatomi Iijima , Kousuke Umeda , Daisuke Kondoh, Baldorj Pagmadulam , Ahmed M Abdou, Yutaka Suzuki, Shun-Ichi Ohba, Kunio Isshiki, Tomoyuki Kimura, Yumiko Kubota, Ryuichi Sawa, Coh-Ichi Nihei and Yoshifumi Nishikawa The Journal of Infectious Diseases 2020 221 766–774
1α-25(OH)2D3 regulates agrin-induced acetylcholine receptor clustering through upregulation of rapsyn expression in C2C12 myotubes.
M. Arakawa and A. Wagatsuma. Biochem. Biophys. Res. Commun. 2020 525 80-86
Antibody-drug conjugates using mouse-canine chimeric anti-dog podoplanin antibody exerts antitumor activity in a mouse xenograft model. Y. Kato, Y. Ito, T. Ohishi, M. Kawada, T. Nakamura, Y. Sayama, M. Sano, T. Asano, M. Yanaka, S. Okamoto, S. Handa, Y. Komatsu, J. Takei and MK. Kaneko. Monoclon Antib Immunodiagn Immunother. 2020 39 37-44
Tumor-derived exosomes in the regulation of macrophage polarization. MS. Baig, A. Roy, S. Rajpoot, D. Liu, R. Savai, S. Banerjee, M. Kawada, SM. Faisal, R. Saluja, U. Saqib, T. Ohishi and KK. Wary. Inflamm Res. 2020 69 435-451
Inhibition of mitochondria ATP synthase suppresses prostate cancer growth through reduced insulin-like growth factor-1 secretion by prostate stromal cells. T. Ohishi, H. Abe, C. Sakashita, U. Saqib, MS. Baig, SI. Ohba, H. Inoue, T. Watanabe, M. Shibasaki and M. Kawada. Int J Cancer. 2020 146 3474-3484
Catalytic asymmetric 1,3-dipolar cycloaddition of α,β-unsaturated amide and azomethine imine. Z. Li, N. Kumagai and M. Shibasaki Chem. Pharm. Bull. 2020 68 552-554
Potent Antibiotics Active against Multidrug-Resistant Gram-Negative Bacteria.
Y. Otsuka Chem. Pharm. Bull. 2020 68 182-190
(2R,3S)-3,4,4,4-Tetrafluorovaline: a fluorinated bioisostere of isoleucine. L. Brewitz, H. Noda, N. Kumagai and M. Shibasaki Eur. J. Org. 2020 2020 1745-1752
A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. J. Takei, MK. Kaneko, T. Ohishi, M. Kawada, H. Harada and Y. Kato Oncol. Lett. 2020 19 2809-2816
A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety.
Y. Kohda, S. Sakamoto, Y. Otsuka, R. Sawa, Y. Kubota, M. Igarashi, H. Muramatsu, M. Iijima and M. Kawada
J. Antibiot. 2020 73 167-170,https://doi.org/10.1038/s41429-019-0258-9