論文一覧
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| Title | Authors | Journal | Year | Vol | Pages |
|---|---|---|---|---|---|
| Direct catalytic asymmetric addition of α-fluoronitriles to aldehydes. |
P. V. Balaji, Z. Li, A. Saito, N. Kumagai and M. Shibasaki | Chem. Eur. J. | 2020 | Accepted | |
| A cancer-specific anti-podocalyxin monoclonal antibody (60-mG 2a-f) exerts antitumor effects in mouse xenograft models of pancreatic carcinoma. |
M. K. Kaneko, T. Ohishi, M. Kawada and Y. Kato | Biochem. Biophys. Rep. | 2020 | Oct 10;24:100826. | doi: 10.1016/j.bbrep.2020.100826. |
| Development of core-fucose-deficient humanized and chimeric anti-human podoplanin antibodies. |
M. K. Kaneko, T. Ohishi, T. Nakamura, H. Inoue, J. Takei, M. Sano, T. Asano, Y. Sayama, H. Hosono, H. Suzuki, M. Kawada and Y. Kato | Monoclon. Antibodies Immunodiagn. Immunother. | 2020 | 39(5) | 167-174 doi: 10.1089/mab.2020.0019. |
| Anti-cancer effects of green tea epigallocatchin-3-gallate and coffee chlorogenic acid. |
S. Hayakawa, T. Ohishi, N. Miyoshi, Y. Oishi, Y. Nakamura and M. Isemura | Molecules | 2020 | 25 | Accepted doi: 10.3390/molecules25194553. |
| Catalytic asymmetric total synthesis of leucinostatin A. |
T. Watanabe, H. Abe and M. Shibasaki | Chem. Rec. | 2020 | Accepted | |
| A defucosylated anti‑CD44 monoclonal antibody 5‑mG2a‑f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma. |
J. Takei, M. K. Kaneko, T. Ohishi, H. Hosono, T. Nakamura, M. Yanaka, M. Sano, T. Asano, Y. Sayama, M. Kawada, H. Harada and Y. Kato | Oncol. Rep. | 2020 | 44 | 1949-1960 |
| Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition. |
T. Onodera, I. Momose, H. Adachi, Y. Yamazaki, R. Sawa, SI. Ohba and M. Kawada | J. Biol. Chem. | 2020 | Accepted | |
| A defucosylated anti-PD-L1 monoclonal antibody 13-mG 2a-f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma. | J. Takei, T. Ohishi, M. K. Kaneko, H. Harada, M. Kawada and Y. Kato | Biochem Biophys Rep. | 2020 | Accepted | doi: 10.1016/j.bbrep.2020.100801. |
| New chloptosins B and C from an Embleya strain exhibit synergistic activity against methicillin-resistant Staphylococcus aureus when combined with co-producing compound L-156,602. | H. Hashizume, S. Harada, R. Sawa, K. Iijima, Y. Kubota, Y. Shibuya, R. Nagasaka, M. Hatano and M. Igarashi | J. Antibiot. | 2020 | Accepted | |
| O-Benzoylhydroxylamines as alkyl nitrene precursors: synthesis of saturated N-heterocycles from primary amines. | H. Noda, Y. Asada and M. Shibasaki | Org. Lett. | 2020 | Accepted | |
| Anti‑EpCAM monoclonal antibody exerts antitumor activity against oral squamous cell carcinomas. |
M. K. Kaneko, T. Ohishi, J. Takei, M. Sano, T. Nakamura, H. Hosono, M. Yanaka, T. Asano, Y. Sayama, H. Harada, M. Kawada, Y. Kato | Oncol Rep. | 2020 | 44 | 2517-2526, doi: 10.3892/or.2020.7808. |
| The anti-EGFR monoclonal antibody 134-mG2a exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma. | H. Hosono, J. Takei, T. Ohishi, M. Sano, T. Asano, Y. Sayama, T. Nakamura, M. Yanaka, M. Kawada, H. Harada, MK. Kaneko and Y. Kato | Int. J. Mol. Med. | 2020 | 46(4) | 1443-1452 |
| Anti-metastatic activity of an anti-EGFR monoclonal antibody against metastatic colorectal cancer with KRAS p.G13D mutation. | T. Ohishi, Y. Kato, MK. Kaneko, SI. Ohba, H. Inoue, A. Harakawa and M. Kawada | Int. J. Mol. Sci. | 2020 | 21(17):E6037 | doi: 10.3390/ijms21176037, 2020 |
| The different faces of [Ru(bpy)3Cl2] and fac[Ir(ppy)3] photocatalysts: redox potential controlled synthesis of sulfonylated fluorenes and pyrroloindoles from unactivated olefins and sulfonyl chlorides. |
S. K. Pagire, N. Kumagai and M. Shibasaki | Org. Lett. | 2020 | Accepted | |
| H 2 Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts. |
J. Takei, MK. Kaneko, T. Ohishi, M. Kawada, H. Harada and Y. Kato | Exp. Ther. Med. | 2020 | 20 | 846-853 |
| An antihuman epidermal growth factor receptor 2 monoclonal antibody (H₂Mab-19) exerts antitumor activity in glioblastoma xenograft models. |
Y. Kato, T. Ohishi, J. Takei, T. Nakamura, M. Kawada and MK. Kaneko | Monoclon. Antibodies Immunodiagn. Immunother. | 2020 | 39 | 135-139 |
| ボロン酸を利用したがん分子標的治療薬の開発 | 百瀬 功、渡辺 匠 | ファルマシア | 2020 | 56 | 416-420 |
| Interferon-induced transmembrane protein 1 (IFITM1) promotes distant metastasis of small cell lung cancer. | S. Sakamoto, H. Inoue, Y. Kohda, S. Ohba, T. Mizutani, and M. Kawada | Int. J. Mol. Sci. | 2020 | 21 | 4934 |
| Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes. | K. Mochida, A. Yamasaki, K. Matoba, H. Kirisako, N. N. Noda and H. Nakatogawa. | Nat. Commun. | 2020 | 11 | 3306 |
| Liquid-liquid phase separation in autophagy. | N. N. Noda, Z. Wang and H. Zhang. | J. Cell Biol. | 2020 | 219 | e202004062 |
| 天然変性タンパク質によるオートファジー始動液滴の形成 | 藤岡優子、野田展生 | 生物物理 | 2020 | 60 | 171-173 |
| An anti-human epidermal growth factor receptor 2 monoclonal antibody H2Mab-19 exerts antitumor activity in mouse colon cancer xenografts. | Y. Kato, T. Ohishi, J. Takai, T. Nakamura, M. Sano, T. Asano, Y. Sayama, H. Hosono, M. Kawada and MK. Kaneko | Monoclon Antib Immunodiagn Immunother. | 2020 | 39 | 123-128 |
| Direct catalytic asymmetric and anti-selective vinylogous addition of butenolides to chromones. | J. Cui, N. Kumagai, T. Watanabe and M. Shibasaki | Chemical Science. | 2020 | 11 | 7170-7176 |
| カレントトピックス「液－液相分離によるオートファゴソームの形成部位の構築」 |
藤岡優子、野田展生 | 実験医学 | 2020 | 38 | 1354-1357 |
| H2Mab-19 anti-human epidermal growth factor receptor 2 monoclonal antibody therapy exerts antitumor activity in pancreatic cancer xenograft models. | Y. Kato, T. Ohishi, M. Sano, T. Asano, Y. Sayama, Y. Takei, M. Kawada and MK. Kaneko | Monoclon Antib Immunodiagn Immunother. | 2020 | 39 | 61-65 |
| Liquidity is a critical determinant for selective autophagy of protein condensates. | A. Yamasaki, J. M. Alam, D. Noshiro, E. Hirata, Y. Fujioka, K. Suzuki, Y. Ohsumi and N. N. Noda | Mol. Cell. | 2020 | 77 | 1163-1175 |
| Phase separation organizes the site of autophagosome formation. | Y. Fujioka, J. M. Alam, D. Noshiro, K. Mouri, T. Ando, Y. Okada, A.I. May, R. L. Knorr, K. Suzuki, Y. Ohsumi and N. N. Noda | Nature. | 2020 | 578 | 301-305 |
| Human ATG2B possesses a lipid transfer activity which is accelerated by negatively charged lipids and WIPI4. |
T. Osawa, Y. Ishii and N. N. Noda | Genes Cells. |
2020 | 25 | 65-70 |
| 柔らかい構造の可視化①LLPSと膜動態を例に |
能代大輔、野田展生 | 実験医学 | 2020 | 38 | 84-89 |
| 選択的オートファジーの構造生物学的基盤 | 野田展生 | 医学のあゆみ | 2020 | 272 | 769-775 |
| オートファゴソーム膜の供給③：蛋白質依存的な隔離膜への脂質供給機構 | 大澤拓生 | 医学のあゆみ | 2020 | 272 | 730-736 |
| オートファジーと液－液相分離 |
藤岡優子 | 医学のあゆみ | 2020 | 272 | 763-768 |
| Introduction of a 7-aza-6-MeO-indoline auxiliary in Lewis-acid/photoredox cooperative catalysis: highly enantioselective aminomethylation of α,β-unsaturated amides. |
S. Kisan Pagire, N. Kumagai and M. Shibasaki | Chemical Science | 2020 | 11 | 5168-5174 |
| Metacytofilin Is a Potent Therapeutic Drug Candidate for Toxoplasmosis | Arpron Leesombun , Masatomi Iijima , Kousuke Umeda , Daisuke Kondoh, Baldorj Pagmadulam , Ahmed M Abdou, Yutaka Suzuki, Shun-Ichi Ohba, Kunio Isshiki, Tomoyuki Kimura, Yumiko Kubota, Ryuichi Sawa, Coh-Ichi Nihei and Yoshifumi Nishikawa | The Journal of Infectious Diseases | 2020 | 221 | 766–774 |
| 1α-25(OH)2D3 regulates agrin-induced acetylcholine receptor clustering through upregulation of rapsyn expression in C2C12 myotubes. |
M. Arakawa and A. Wagatsuma. | Biochem. Biophys. Res. Commun. | 2020 | 525 | 80-86 |
| Antibody-drug conjugates using mouse-canine chimeric anti-dog podoplanin antibody exerts antitumor activity in a mouse xenograft model. | Y. Kato, Y. Ito, T. Ohishi, M. Kawada, T. Nakamura, Y. Sayama, M. Sano, T. Asano, M. Yanaka, S. Okamoto, S. Handa, Y. Komatsu, J. Takei and MK. Kaneko. | Monoclon Antib Immunodiagn Immunother. | 2020 | 39 | 37-44 |
| Tumor-derived exosomes in the regulation of macrophage polarization. | MS. Baig, A. Roy, S. Rajpoot, D. Liu, R. Savai, S. Banerjee, M. Kawada, SM. Faisal, R. Saluja, U. Saqib, T. Ohishi and KK. Wary. | Inflamm Res. | 2020 | 69 | 435-451 |
| Inhibition of mitochondria ATP synthase suppresses prostate cancer growth through reduced insulin-like growth factor-1 secretion by prostate stromal cells. | T. Ohishi, H. Abe, C. Sakashita, U. Saqib, MS. Baig, SI. Ohba, H. Inoue, T. Watanabe, M. Shibasaki and M. Kawada. | Int J Cancer. | 2020 | 146 | 3474-3484 |
| Catalytic asymmetric 1,3-dipolar cycloaddition of α,β-unsaturated amide and azomethine imine. | Z. Li, N. Kumagai and M. Shibasaki | Chem. Pharm. Bull. | 2020 | 68 | 552-554 |
| Potent Antibiotics Active against Multidrug-Resistant Gram-Negative Bacteria. |
Y. Otsuka | Chem. Pharm. Bull. | 2020 | 68 | 182-190 |
| (2R,3S)-3,4,4,4-Tetrafluorovaline: a fluorinated bioisostere of isoleucine. | L. Brewitz, H. Noda, N. Kumagai and M. Shibasaki | Eur. J. Org. | 2020 | 2020 | 1745-1752 |
| A novel anti-EGFR monoclonal antibody (EMab-17) exerts antitumor activity against oral squamous cell carcinomas via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. | J. Takei, MK. Kaneko, T. Ohishi, M. Kawada, H. Harada and Y. Kato | Oncol. Lett. | 2020 | 19 | 2809-2816 |
| A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-L-talopyranose moiety. |
Y. Kohda, S. Sakamoto, Y. Otsuka, R. Sawa, Y. Kubota, M. Igarashi, H. Muramatsu, M. Iijima and M. Kawada |
J. Antibiot. | 2020 | 73 | 167-170,https://doi.org/10.1038/s41429-019-0258-9 |