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Discovery of a novel factor that promotes mitochondrial fission

With support from JST (Japan Science and Technology Agency), JSPS (Japan Society for the Promotion of Science), the Takeda Science Foundation, and other organizations, Nobuo N. Noda, a Specially Appointed Researcher in the Laboratory of Structural Biology at our institute (and Professor at Hokkaido University), and Tatsuro Maruyama, a Researcher in the same laboratory, in collaboration with research groups at Kyushu University, Hokkaido University, Yokohama City University, and Niigata University, have discovered a novel factor that promotes mitochondrial fission. The findings were published online in the international scientific journal EMBO Reports on January 13, 2026.For more details, click here. (in Japanese)

Selective Glycosylation Method Develops New Therapeutic Candidate for Pulmonary Non-tuberculous Mycobacterial Infection

【News Release】Dr. Masayuki Igarashi, Head of the Microbiology Laboratory at our Institute, in collaboration with Associate Professor Daisuke Takahashi, Professor Kazunobu Toyoshima of Keio University, and Assistant Professor Takeshi Yokoyama of Tohoku University, has developed a new chemical modification method for the macrolide antibiotic azithromycin (AZM), and by utilizing this method, they succeeded in creating a new lead compound against pulmonary non-tuberculous mycobacterial (NTM) disease.The research results were published in the American scientific journal Science Advances on March 5, 2025. Selective Glycosylation Method Develops New Therapeutic Candidate for Pulmonary Non-tuberculous Mycobacterial Infection-Expectations for the development of new antimicrobial agents effective against drug-resistant bacteriamore (In Japanese)

Recruitment of postdoctoral researchers

The Institute of Microbial Chemistry (IMC) invites applications for Postdoctoral Research Fellowships. We are looking for researchers who are interested in and are enthusiastic about some of the research themes. We welcome applicants from varied backgrounds, regardless of the fields of research. more

Announcement of JA Ōmura Award 2023 Winner

We are pleased to announce that our researchers have been awarded the JA Ōmura Award 2023. Tomoyuki Kimura (Senior Researcher, Molecular Structure Analysis Division))details click here. (External websites.)

Added Osada Unit website

A page for the Osada Unit, led by Dr. Hiroyuki Osada, Project Director of the Laboratory of Microbiology, has been added to the Laboratories page.

Personnel Announcement

Dr. Hiroyuki Osada and Dr. Yoshiya Oda were appointed as Head of the Institute of Microbial Chemistry.

Announcement of Organizational Changes

The Laboratory of Synthetic Organic Chemistry and the Laboratory of Medicinal Chemistry were merged to form the Laboratory of Chemistry.