Selective Glycosylation Method Develops New Therapeutic Candidate for Pulmonary Non-tuberculous Mycobacterial Infection
March 6, 2025
【News Release】Dr. Masayuki Igarashi, Head of the Microbiology Laboratory at our Institute, in collaboration with Associate Professor Daisuke Takahashi, Professor Kazunobu Toyoshima of Keio University, and Assistant Professor Takeshi Yokoyama of Tohoku University, has developed a new chemical modification method for the macrolide antibiotic azithromycin (AZM), and by utilizing this method, they succeeded in creating a new lead compound against pulmonary non-tuberculous mycobacterial (NTM) disease.The research results were published in the American scientific journal Science Advances on March 5, 2025. Selective Glycosylation Method Develops New Therapeutic Candidate for Pulmonary Non-tuberculous Mycobacterial Infection-Expectations for the development of new antimicrobial agents effective against drug-resistant bacteriamore (In Japanese)
