Research Outline

At the Laboratory of Molecular Structure Analysis, we use analytical apparatus such as nuclear magnetic resonance (NMR), mass spectrometry (MS), and X-ray crystal structure analysis for the structural analysis of a wide range of biologically active substances found in assay systems, in addition to derivatives of these substances and synthetic compounds.

Theme

• Metabolomic analysis of microbial metabolites and structural studies of novel bioactive substances

Theme

1. Metabolomic analysis of microbial metabolites and structural studies of novel bioactive substances

Microbial secondary metabolites have diverse chemical structures and biological activities. The discovery of new bioactive substances has become very difficult because of the numerous types of materials that have been found by intensive screening over a long period of time. We have carried out metabolome analysis using high resolution and high accuracy LC-MS apparatus, and rapid identification of known substances (dereplication) and structural analysis of novel bioactive substances.

 list of equipment 

Members

      Researcher

  Shinya Adachi
  Tomoyuki Kimura
  Tatsuro Maruyama (Concurrent)
  Yumiko Kubota

One Technical Staff