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Apr. 25. 2012
日本薬学会第132回年会において、当研究室の川戸勇士と野尻明宏が学生優秀発表賞を受賞しました。
July 1. 2011第21回光学活性シンポジウムの情報を掲載しました。
(HPはこちら)
柴崎教授が有機合成化学協会特別賞を受賞しました。
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Apr. 25. 2012
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TOP
Recent publication

Concise Enantioselective Synthesis of Duloxetine via Direct Catalytic Asymmetric Aldol Reaction of Thioamide"
Suzuki, Y.; Iwata, M.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
J. Org. Chem. 2012, ASAP
"Catalytic Asymmetric Total Synthesis of Chimonanthine, Folicanthine, and Calycanthine through Double Michael Reaction of Bisoxindole"
Mitsunuma, H.; Shibasaki, M.; Kanai, M.; Matsunaga, S.
Angew. Chem. Int. Ed. 2012, Early View

"A Direct Catalytic Asymmetric Aldol Reaction of α-Sulfanyl Lactones: Efficient Synthesis of SPT Inhibitors"
Takechi, S.; Yasuda, S.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 4218.
"Asymmetric Synthesis of Dihydropyranones from Ynones by Sequential Copper(I)-Catalyzed Direct Aldol and Silver(I)-Catalyzed Oxy-Michael Reactions"
Shi, S.- L.; Kanai, M.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 3932.

"Catalytic Enantioselective Desymmetrization of meso-Glutaric Anhydrides Using a Stable Ni2-Schiff Base Catalyst"
Gopinath, P.; Watanabe, T.; Shibasaki, M.
Org. Lett. 2012, 14, 1358.

"Reversible Heterochiral Aggregation/Dissociation of Bis(2-hydroxyphenyl)diamides Driven by UV/Vis Irradiation"
Nojiri, A.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 2137.

"Catalytic Asymmetric anti-Selective Nitroaldol Reaction En Route to Zanamivir"
Nitabaru, T.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 1644. (selected as a hot paper)

"Intermediate as Catalyst: Catalytic Asymmetric Conjugate Addition of Nitroalkanes to α,β-Unsaturated Thioamides"
Ogawa, T.; Mouri, S.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Org. Lett. 2012, 14, 110.

"Direct Catalytic Asymmetric Intramolecular Conjugate Addition of Thioamide to α,β-Unsaturated Ester"
Suzuki, Y.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Chem. Eur. J. 2011, 17, 11998.

"A simplified catalytic system for direct catalytic asymmetric aldol reaction of thioamides; application to an enantioselective synthesis of atorvastatin"
Kawato, Y.; Iwata, M.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Tetrahedron 2011, 67, 6539.

"Asymmetric Synthesis of Isothiazoles through Cu Catalysis: Direct Catalytic Asymmetric Conjugate Addition of Allyl Cyanide to α,β-Unstaurated Thioamides"
Yanagida, Y.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2011, 50, 7910.

"La/Ag Heterobimetallic Cooperative Catalysis: A Catalytic Asymmetric Conia-Ene Reaction"
Matsuzawa, A.; Mashiko, T.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2011, 50, 7616.
highlighted by Synfacts 2011, 1222.





