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当研究室では博士研究員を募集しています。興味ある方はこちらまでご連絡下さい。

News


Apr. 25. 2012

日本薬学会第132回年会において、当研究室の川戸勇士と野尻明宏が学生優秀発表賞を受賞しました。

July 1. 2011

第21回光学活性シンポジウムの情報を掲載しました。
HPはこちら

Sep. 29. 2010

柴崎教授が有機合成化学協会特別賞を受賞しました。


Updates


Apr. 25. 2012

Publication 更新

Apr. 1. 2012

Publication 更新
LabInfo - Lab member 更新

Jan. 11. 2012

Publication 更新

Nov. 24. 2011

Publication 更新

Nov. 16. 2011

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LabInfo - Gallery(snap) 更新

July 6. 2011

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Jun. 9. 2011

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May 10. 2011

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TOP

Recent publication

Concise Enantioselective Synthesis of Duloxetine via Direct Catalytic Asymmetric Aldol Reaction of Thioamide"
Suzuki, Y.; Iwata, M.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
J. Org. Chem. 2012, ASAP


"Catalytic Asymmetric Total Synthesis of Chimonanthine, Folicanthine, and Calycanthine through Double Michael Reaction of Bisoxindole"
Mitsunuma, H.; Shibasaki, M.; Kanai, M.; Matsunaga, S.
Angew. Chem. Int. Ed. 2012, Early View


"A Direct Catalytic Asymmetric Aldol Reaction of α-Sulfanyl Lactones: Efficient Synthesis of SPT Inhibitors"
Takechi, S.; Yasuda, S.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 4218.


"Asymmetric Synthesis of Dihydropyranones from Ynones by Sequential Copper(I)-Catalyzed Direct Aldol and Silver(I)-Catalyzed Oxy-Michael Reactions"
Shi, S.- L.; Kanai, M.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 3932.


"Catalytic Enantioselective Desymmetrization of meso-Glutaric Anhydrides Using a Stable Ni2-Schiff Base Catalyst"
Gopinath, P.; Watanabe, T.; Shibasaki, M.
Org. Lett. 2012, 14, 1358.


"Reversible Heterochiral Aggregation/Dissociation of Bis(2-hydroxyphenyl)diamides Driven by UV/Vis Irradiation"
Nojiri, A.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 2137.


"Catalytic Asymmetric anti-Selective Nitroaldol Reaction En Route to Zanamivir"
Nitabaru, T.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2012, 51, 1644. (selected as a hot paper)


"Intermediate as Catalyst: Catalytic Asymmetric Conjugate Addition of Nitroalkanes to α,β-Unsaturated Thioamides"
Ogawa, T.; Mouri, S.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Org. Lett. 2012, 14, 110.


"Direct Catalytic Asymmetric Intramolecular Conjugate Addition of Thioamide to α,β-Unsaturated Ester"
Suzuki, Y.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Chem. Eur. J. 2011, 17, 11998.


"A simplified catalytic system for direct catalytic asymmetric aldol reaction of thioamides; application to an enantioselective synthesis of atorvastatin"
Kawato, Y.; Iwata, M.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Tetrahedron 2011, 67, 6539.


"Asymmetric Synthesis of Isothiazoles through Cu Catalysis: Direct Catalytic Asymmetric Conjugate Addition of Allyl Cyanide to α,β-Unstaurated Thioamides"
Yanagida, Y.; Yazaki, R.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2011, 50, 7910.


"La/Ag Heterobimetallic Cooperative Catalysis: A Catalytic Asymmetric Conia-Ene Reaction"
Matsuzawa, A.; Mashiko, T.; Kumagai, N.; Shibasaki, M.
Angew. Chem. Int. Ed. 2011, 50, 7616.   highlighted by Synfacts 2011, 1222.