基盤生物研究部

研究業績

Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish.
Y. Mishima, A. Fukao, T. Kishimoto, H. Sakamoto, T. Fujiwara, K. Inoue
Proc.Natl.Acad.Sci.USA, 2011, in press
Functional and direct interaction between the RNA binding protein HuD and active Akt1.
T. Fujiwara, A. Fukao, Y. Sasano, H. Matsuzaki, U. Kikkawa, H. Imataka, K.
Inoue, S. Endo, N. Sonenberg, C. Thoma, H. Sakamoto.
Nucleic Acids Res. 2011 Nov 10. Epub ahead of print
Sorting of influenza A virus RNA genome segments after nuclear export.
N. Takizawa, M. Kumakura, K. Takeuchi, N. Kobayashi and K. Nagata.
Virology 2010, 401, 248-256.
Mechanisms of translational regulation by a human eIF5-mimic protein.

CR. Singh, R. Watanabe, D. Zhou, MD. Jennings, A. Fukao, B. Lee, Y. Ikeda, JA. Chiorini, SG. Campbell, MP. Ashe, T. Fujiwara, RC. Wek, GD. Pavitt and K. Asano.
Nucleic Acids Res. 2011 Oct 1;39(19):8314-28
Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.
Y. Fujiwara, K. Kasashima, K. Saito, M. Fukuda, A. Fukao, Y. Sasano, K. Inoue, T. Fujiwara and H. Sakamoto.
Biochimie. 2011, 93, 817-822.
Single-embryo metabolomics and systematic prediction of developmental stage in zebrafish.
S. Hayashi, M. Yoshida, T. Fujiwara, S. Maegawa and E. Fukusaki.
Z Naturforsch C. 2011, 66, 191-198.
Dynamic profiling of mRNA turnover reveals gene-specific and system-wide regulation of mRNA decay.
S. E. Munchel, R. K. Shultzaberger, N. Takizawa and K. Weis.
Mol Biol Cell. 2011, 22, 2787-2795.
Crucial role of the influenza virus NS2 (NEP) C-terminal domain in M1 binding and nuclear export of vRNP.
T. Shimizu, N. Takizawa, K. Watanabe, K. Nagata and N. Kobayashi.
FEBS Lett. 2011, 585, 41-46.
Poliomyelitis.
S. Koike and A. Nomoto.
The Picornaviruses. 2010, 339-351.
2A protease is not a prerequisite for poliovirus replication.
H. Igarashi, Y. Yoshino, M. Miyazawa, H. Horie, S. Ohka and A. Nomoto.
J Virol. 2010, 84, 5947-5957.
A small nucleolar RNA functions in rRNA processing in Caenorhabditis elegans.
Y. Hokii, Y. Sasano, M. Sato, H. Sakamoto, K. Sakata, R. Shingai, A. Taneda, S. Oka, H.
Himeno, A. Muto, T. Fujiwara and C. Ushida.
Nucleic Acids Res. 2010, 38, 5909-5918.
Involvement of vesicular trafficking system in membrane targeting of the progeny influenza virus genome.
S. Jo, A. Kawaguchi, N. Takizawa, Y. Morikawa, F. Momose and K. Nagata.
Microbes Infect. 2010, 12, 1079-1084.
Distribution of Kakugo virus and its effects on the gene expression profile in the brain of the worker honeybee Apis mellifera L.
T. Fujiyuki, E. Matsuzaka, T. Nakaoka, H. Takeuchi, A. Wakamoto, S. Ohka, K. Sekimizu, A. Nomoto and T. Kubo.
J Virol. 2009, 83, 11560-11568.
Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons.
S. Ohka, M. Sakai, S. Bohnert, H. Igarashi, K. Deinhardt, G. Schiavo and A. Nomoto.
J Virol. 2009, 83, 4995-5004.
The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and
eIF4A-dependent manner.
A. Fukao, Y. Sasano, H. Imataka, K. Inoue, H. Sakamoto, N. Sonenberg, C. Thoma and T. Fujiwara.
Mol Cell. 2009, 36, 1007-1017.
A novel application of metabolomics in vertebrate development.
S. Hayashi, S. Akiyama, Y. Tamaru, Y. Takeda, T. Fujiwara, K. Inoue, A. Kobayashi, S.
Maegawa and E. Fukusaki.
Biochem Biophys Res Commun. 2009, 386, 268-272.
DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish.
Y. Takeda, Y. Mishima, T. Fujiwara, H. Sakamoto and K. Inoue.
PLoS One. 2009, 4, e7513.
Induction of immune responses to a human immunodeficiency virus type 1 epitope by novel chimeric influenza viruses.
N. Takizawa, M. Morita, K. Adachi, K. Watanabe and N. Kobayashi.
Drug Discov. Ther. 2009, 3, 252-259.
Screening of detergents for solubilization, purification and crystallization of membrane
proteins: a case study on succinate:ubiquinone oxidoreductase from Escherichia coli.
H. Shimizu, C. Nihei, D. K. Inaoka, T. Mogi, K. Kita and S. Harada.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008, 64, 858-862.
Comparative aspects on the role of polypyrimidine tract-binding protein in internal
initiation of hepatitis C virus and picornavirus RNAs.
T. Nishimura, M. Saito, T. Takano, A. Nomoto, M. Kohara and K. Tsukiyama-Kohara.
Comp Immunol Microbiol Infect Dis. 2008, 31, 435-448.
WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and
teleost organ development.
N. Iwanami, T. Higuchi, Y. Sasano, T. Fujiwara, V. Q. Hoa, M. Okada, S. R. Talukder, S.
Kunimatsu, J. Li, F. Saito, C. Bhattacharya, A. Matin, T. Sasaki, N. Shimizu, H. Mitani, H. Himmelbauer, A. Momoi, H. Kondoh, M. Furutani-Seiki and Y. Takahama.
PLoS Genet. 2008, 4, e1000171.
Biochemical selenocysteine synthesis and the phylogenic study.
T. Mizutani, T. Osaka, T. Fujiwara and M. Shahidzzman.
Yakugaku Zasshi. 2008, 128, 989-996.
Distribution of U3 small nucleolar RNA and fibrillarin during early embryogenesis in
Caenorhabditis elegans.
Y. Sasano, Y. Hokii, K. Inoue, H. Sakamoto, C. Ushida and T. Fujiwara.
Biochimie. 2008, 90, 898-907.
Efficient propagation of betanodavirus in a murine astrocytoma cell line.
N. Takizawa, K. Adachi, T. Ichinose and N. Kobayashi.
Virus Res. 2008, 136, 206-210.
Establishment of reverse genetics system of betanodavirus for the efficient recovery of
infectious particles.
N. Takizawa, K. Adachi and N. Kobayashi.
J Virol Methods. 2008, 151, 271-276.
Hsc70 regulates the nuclear export but not the import of influenza viral RNP: A possible
target for the development of anti-influenza virus drugs.
K. Watanabe, N. Takizawa, S. Noda, F. Tsukahara, Y. Maru and N. Kobayashi.
Drug Discov. Ther. 2008, 2, 77-84.
Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein.
T. Munakata, Y. Liang, S. Kim, D. R. McGivern, J. Huibregtse, A. Nomoto and S. M. Lemon.
PLoS Pathog. 2007, 3, 1335-1347.
Establishment of a poliovirus oral infection system in human poliovirus receptor-expressing transgenic mice that are deficient in alpha/beta interferon receptor.
S. Ohka, H. Igarashi, N. Nagata, M. Sakai, S. Koike, T. Nochi, H. Kiyono and A. Nomoto.
J Virol. 2007, 81, 7902-7912.
Tissue-specific splicing regulator Fox-1 induces exon skipping by interfering E complex
formation on the downstream intron of human F1gamma gene.
K. Fukumura, A. Kato, Y. Jin, T. Ideue, T. Hirose, N. Kataoka, T. Fujiwara, H. Sakamoto and K. Inoue.
Nucleic Acids Res. 2007, 35, 5303-5311.
Inhibition of betanodavirus infection by inhibitors of endosomal acidification.
K. Adachi, T. Ichinose, N. Takizawa, K. Watanabe, K. Kitazato and N. Kobayashi.
Arch Virol. 2007, 152, 2217-2224.