Substances discovered by the MCRF and launched
| Substance | Use | Discovered | Marketed | |
|---|---|---|---|---|
| 1. | Kanamycin | Antibacterial chemotherapeutic drug | 1957 | 1958 |
| 2. | Bekanamycin (Kanamycin B) |
Antibacterial chemotherapeutic drug | 1957 | 1969 |
| 3. | Bleomycin | Anticancer chemotherapeutic drug | 1965 | 1969 |
| 4. | Kasugamycin | Agrochemical for rice blast disease | 1965 | 1970 |
| 5. | Josamycin | Antibacterial chemotherapeutic drug | 1967 | 1970 |
| 6. | Dibekacin (Pamimycin) |
Antibacterial chemotherapeutic drug | 1971 | 1975 |
| 7. | Peplomycin | Anticancer chemotherapeutic drug | 1978 | 1981 |
| 8. | Aclarubicin | Anticancer chemotherapeutic drug | 1975 | 1982 |
| 9. | Ubenimex (Bestatin) |
Anticancer chemotherapeutic drug | 1976 | 1987 |
| 10. | Pirarubicin | Anticancer chemotherapeutic drug | 1979 | 1988 |
| 11. | Aivlosin | Antibacterial veterinary medicine | 1979 | 1989 |
| 12. | Arbekacin (Habekacin) |
Antibacterial chemotherapeutic drug | 1973 | 1990 |
| 13. | Gusperimus | Immunosuppressive agent | 1982 | 1994 |
| 14. | Zuprevo (Tildipirosin) |
Antibacterial veterinary medicine | 2000 | 2011 |
Commercially available enzyme inhibitors used as reagents
| Substance | Enzyme inhibitor | Discovered | |
|---|---|---|---|
| 1. | Leupeptin | Serine-Cysteine proteinase | 1969 |
| 2. | Pepstatin | Aspartic proteinase | 1970 |
| 3. | Chymostatin | Serine-Cysteine proteinase | 1970 |
| 4. | Antipain | Serine-Cysteine proteinase | 1972 |
| 5. | Phosphoramidon | Metal proteinase | 1973 |
| 6. | Elastatinal | Serine-Cysteine proteinase | 1973 |
| 7. | Amastatin | Aminopeptidase | 1978 |
| 8. | Ebelacton | Aminopeptidase | 1980 |
| 9. | Arphamenines | Aminopeptidase | 1983 |
| 10. | Diprotin A | Dipeptidylaminopeptidase | 1984 |
| 11. | Actinonin | Aminopeptidase | 1985 |
| 12. | Foroxymithine | Dipeptidylaminopeptidase | 1985 |
| 13. | Leuhistin | Aminopeptidase | 1990 |
